An NOAA research team is sent to a remote Alaskan island to discover why The entire population of Cook Inlet Beluga whales, an endangered species, has gone missing and six of them were mutilated and washed up on shore.
At first glance, it appears that the dead whales were involved in some kind of accident, but after discovery the six, three-thousand-pound carcasses go missing.
They search the bush for clues with the help of the local fish and game warden, but find little evidence. Upon speaking with an old Shaman woman, she says she believes it is the work of a yeti. Searching caves on the island, they discover a ruined meth lab, a poacher’s den, a lot of dead humans, but no whales and no other clues.
After two of their own are killed, they are caught by the remaining poachers and meth dealers. Something large and stealthy starts murdering them. It kills the frantic, fleeing humans in the dark, one by one, as if toying with them. The scientists and the head poacher are the only ones left. They barely make it to safety.
One final search of the caves results in the discovery of the culprit. A forty-five hundred pound genetically enhanced grizzly/polar bear hybrid. Once the scientists report their findings, a military clean-up crew arrives to take out the bear. ...and the scientists who now know too much.
The secret military containment squad of six use the scientists to hunt the bear, but they underestimate her. She sends her cub to her cave as a distraction and picks off the soldiers, silently, one-by-one.
With only the Colonel left, he blows up the cave with the bear and her cub in it. He celebrates too early. The bear and cub survive the explosion, break out of the cave and kill him.
The scientists and game warden flee to his cabin to regroup, but the angry bear follows.
The bear throws a boulder through the roof of the game warden’s cabin, killing one of the scientists, leaving just the game warden and one last scientist.
They concoct a hasty, battlefield plan to blow up the bear using a crate of dynamite and the cabin’s propane tank. The bear sniffs around, looking for survivors. The scientist hits the bear with a truck, nudging her near the propane tank. The game warden shoots the dynamite and it explodes, engulfing the entire area in flames.
When he comes to, the last scientist is dead.
But there is no dead bear.
In the final scene the mother bear and her six gigantic cubs swim in the ocean in search for a new home.